xevonta®

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Dialyzer for achieving balance between elimination and retention

xevonta allows for efficient elimination of middle molecules and other uremic toxins while limiting the loss of serum albumin to 1.1±0.2g/ session. This is even the case with our largest 2.3m² surface-area dialyzer, when used under post-dilution HDF conditions using high convective volumes.1

 

Importance of serum albumin

  • Marker for nutritional and inflammatory status of maintenance for dialysis patients2
  • Strong predictor for mortality3

1) Gayrard N et al. Influence of high convection volumes in removal performances of on-line haemodiafiltration (HDF). Nephrol. Dial. Transplant. (2013) 28 (suppl 1): i30-i32.

2) Clinical practice guidelines for nutrition in chronic renal failure. K/DOQI, National Kidney Foundation. Am J Kidney Dis. 2000 Jun; 35(6 suppl. 2): S1-140.

3) Kalantar-Zadeh K et al.: Revisiting mortality predictability of serum albumin in the dialysis population: Time dependency, longitudinal changes and population-attributable fraction.